Injectables / TREATMENT GUIDE
Polynucleotides (PN and PDRN)
Purified DNA fragments, usually from salmon, injected in small amounts to support skin repair, hydration and elasticity, especially in delicate areas such as under the eyes.
- Appointment
- 20 to 30 minutes
- Typical social recovery
- Around a day
- When results may appear
- 3 to 4 weeks into the course
- How long they may last
- 6 to 12 months
- Typical course
- 2 to 4, spaced 2 to 4 weeks
- Relative cost
- $ · Moderate relative cost
Ranges vary by person, product, area and technique. Cost symbols are editorial comparisons—not quotes. Ask for the full course and follow-up cost.
How it works
The fragments appear to signal skin cells toward repair and calm inflammation, encouraging collagen and elastin over a series of sessions. They add no volume.
Four illustrative steps. Select a step to highlight it; the optional anatomy view explains the same mechanism.
Recovery, in practical terms
Small bumps for up to 24 hours.
What it can feel like: Mild.
What people discuss
Under-eye crepiness and darkness, early sun damage, sensitive skin.
Reasons to pause
Fish allergy (check the product source), pregnancy.
This list is not exhaustive. A clinician must assess your health, medications, skin and goals.
Risks worth understanding
- Bumps and bruising
- Allergy is rare but possible
Ask your clinician
- What is the source, and is this product approved for injection here?
- How many sessions before we judge the result?
Availability and regulatory status differ by country. Verify the exact injectable product and indication locally; availability in Europe or Asia does not establish US approval.
Sources, approval context & editorial limits
Product, indication and treatment site must be checked locally.
Sources support regulatory and safety context; not every efficacy claim or range has been independently verified.
Educational information, not medical advice or a personal recommendation. Independent clinical review is pending. A qualified clinician must assess individual suitability. Timings, relative costs and visuals are illustrative, not guarantees.
Read the editorial policyCompare different approaches
Related catalogue tags, not recommendations.
- Injectables
Wrinkle relaxers (neuromodulators)
Tiny injections of botulinum toxin type A that temporarily soften the muscle movements that fold the skin into lines: frown lines, forehead…
Usually minimal recovery - Injectables
Hyaluronic acid fillers
Smooth gels of hyaluronic acid, a sugar your skin already makes, placed under the skin to restore lost volume, add structure or soften deep…
A few days recovery - Injectables
Skin boosters (microdroplet hyaluronic acid)
Thin, lightly cross-linked hyaluronic acid injected in many tiny droplets across the skin, or in a few points that spread, to boost hydration…
Around a day recovery