The powerful combination of naltrexone and bupropion has the potential to revolutionize weight loss.
The combination of naltrexone and bupropion may help boost weight loss. Naltrexone targets the brain’s reward system, while bupropion helps reduce appetite. Together, they may support your weight loss goals.
This treatment is both safe and effective. It may also help lower cortisol levels. People with high cortisol often see fewer food cravings, making this option especially helpful for them.
The combo of naltrexone and bupropion shows strong promise for weight loss. Naltrexone may affect the brain’s reward system, while bupropion helps reduce appetite. Together, they may help you reach your weight loss goals.
Studies show this treatment is safe and effective. It may also lower cortisol levels. For people with high cortisol, it can reduce food cravings, making it especially helpful.
Being overweight is a complex issue that often needs more than one treatment. Diet, exercise, medication, and behavior changes all play a role.
A BMI between 25 and 29.9 is considered overweight. A BMI of 30 or higher is classified as obesity.
Doctors may prescribe Naltrexone/Bupropion after a full health review. Each extended-release tablet has 8 mg of naltrexone and 90 mg of bupropion.
Dosing Schedule:
•Week 1: 1 tablet in the morning
•Week 2: 1 tablet morning and evening
•Week 3: 2 tablets in the morning, 1 in the evening
•Week 4 and beyond: 2 tablets, morning and evening
•Max dose: 4 tablets daily
If a patient hasn’t lost at least 5% of their starting weight after 12 weeks on the full dose, it’s best to stop treatment. Continued use likely won’t lead to further weight loss.
So far, the effect on heart health is unknown. Also, it’s unclear if this drug is safe when used with other weight loss products.
Avoid taking bupropion and naltrexone if you have uncontrolled high blood pressure, a history of seizures, an eating disorder, opioid dependence, or are pregnant. Also, avoid it if you use opioid medications, other forms of bupropion, or if you’ve recently stopped using alcohol, seizure medicine, or sedatives.
Next, always tell your healthcare provider about all your current medications. This includes any new ones or if you’ve recently stopped any, as some drugs can interact with bupropion and naltrexone.
Also, some people may experience suicidal thoughts when starting bupropion. Watch for mood changes and report any new or worsening symptoms to your doctor right away.
Drinking alcohol while taking bupropion increases the risk of seizures. If you drink regularly, talk to your provider before making any changes to your alcohol use. Suddenly stopping alcohol can also trigger seizures while on bupropion.
Follow your provider’s instructions about diet, exercise, and what drinks to avoid. Don’t use other diet pills or weight-loss products unless your provider tells you to.
Finally, never use opioid medications, methadone, heroin, or illegal drugs while taking bupropion and naltrexone. Doing so can cause serious harm, including coma or death.
The typical cost of Bupropion-naltrexone (Contrave) averages between $100 and $300 when purchased without insurance coverage.
